chromosomal mutation

Relationship between chromosomal aberration of germ cells and dominant lethal mutation in male mice after low dosage of X-irradiation

小剂量X射线诱发雄性小鼠生殖细胞染色体畸变与显性致死间关系

The relationship between chromosomal aberration and dominant mutation in spermatocytes of late pachytene phase in male mice after a single X-irridiation was reported.

本文报道了小剂量（0～1.0Gy）x射线单次全身照射雄性小白鼠诱发的精母细胞晚粗线期染色体畸变与显性致死间关系。

The Ames test, Erythrocyte micronucleus assay, Spermatogonial chromosomal aberrations test and In vitro mammalian cell gene mutation test were used.

采用鼠伤寒沙门氏菌回复突变试验（Ames试验）、小鼠骨髓多染红细胞微核试验、小鼠睾丸精母细胞染色体畸变试验、V79细胞基因突变试验来检测有无致突变作用。